Επιστροφή στο Forum : Anarchy Covalex (VPX)
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Για ρίξτε γνώμες ρε παίδες.....Καλο φενετε αλλα δεν μου αρέσει το Diiodo-L-thyronine...Τι το θελαν ρε γαμώτο...Μονο αυτο με χαλάει αλιος θα το επερνα γιατι εχει και καλη τιμουλα....
τσεκαρε το 1ο συστατικο.... 1,3-N-Dipropyl-7-Propargylxanthine
Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors.
Daly JW, Padgett WL, Shamim MT.
A variety of analogues of caffeine and theophylline in which the 1-,3-, and 7-methyl substituents have been replaced with n-propyl, allyl, propargyl, and isobutyl and, in a few cases, with chloroethyl, hydroxyethyl, or benzyl were assessed for potency and selectivity as antagonists at A1- and A2-adenosine receptors in brain tissue. Caffeine and theophylline are nonselective for these receptors. Nearly all of the 22 analogues of caffeine are more potent than caffeine itself at adenosine receptors. Replacement of the 1-methyl moiety with n-propyl, allyl, or propargyl substituent has little effect on potency at the A1 receptor while enhancing potency about 7- to 10-fold at the A2 receptor. 3,7-Di-methyl-1-propylxanthine is only slightly (1.4-fold) more potent than caffeine at the A1 receptor while being 10-fold more potent at the A2 receptor. 1,3-Di-n-propyl-7-methylxanthine is also selective for the A2 receptor, being 8-fold more potent than caffeine at the A1 receptor and 40-fold more potent at the A2 receptor. A number of other caffeine analogues including 3,7-dimethyl-1-n-propylxanthine, 7-allyl-1,3-dimethylxanthine, and 1,3-dimethyl-7-propargylxanthine are also somewhat selective for the A2 receptor. The most potent caffeine analogue was 1,3-di-n-propyl-7-propargylxanthine, which was about 100-fold more potent than caffeine at both A1 and A2 receptors. The 10 theophylline analogues were relatively nonselective except for the 1-ethyl analogue and the 1,3-diallyl analogue, which were selective for the A2 receptor, and the 1,3-di-n-propyl, 1,3-diisobutyl, and 1,3-dibenzyl analogues, which were somewhat selective for the A1 receptor. 1,3-Di-n-propylxanthine was 20-fold more potent than theophylline at the A1 receptor and 5-fold more potent at the A2 receptor.
τσεκαρε το 1ο συστατικο.... 1,3-N-Dipropyl-7-Propargylxanthine
Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors.
Daly JW, Padgett WL, Shamim MT.
A variety of analogues of caffeine and theophylline in which the 1-,3-, and 7-methyl substituents have been replaced with n-propyl, allyl, propargyl, and isobutyl and, in a few cases, with chloroethyl, hydroxyethyl, or benzyl were assessed for potency and selectivity as antagonists at A1- and A2-adenosine receptors in brain tissue. Caffeine and theophylline are nonselective for these receptors. Nearly all of the 22 analogues of caffeine are more potent than caffeine itself at adenosine receptors. Replacement of the 1-methyl moiety with n-propyl, allyl, or propargyl substituent has little effect on potency at the A1 receptor while enhancing potency about 7- to 10-fold at the A2 receptor. 3,7-Di-methyl-1-propylxanthine is only slightly (1.4-fold) more potent than caffeine at the A1 receptor while being 10-fold more potent at the A2 receptor. 1,3-Di-n-propyl-7-methylxanthine is also selective for the A2 receptor, being 8-fold more potent than caffeine at the A1 receptor and 40-fold more potent at the A2 receptor. A number of other caffeine analogues including 3,7-dimethyl-1-n-propylxanthine, 7-allyl-1,3-dimethylxanthine, and 1,3-dimethyl-7-propargylxanthine are also somewhat selective for the A2 receptor. The most potent caffeine analogue was 1,3-di-n-propyl-7-propargylxanthine, which was about 100-fold more potent than caffeine at both A1 and A2 receptors. The 10 theophylline analogues were relatively nonselective except for the 1-ethyl analogue and the 1,3-diallyl analogue, which were selective for the A2 receptor, and the 1,3-di-n-propyl, 1,3-diisobutyl, and 1,3-dibenzyl analogues, which were somewhat selective for the A1 receptor. 1,3-Di-n-propylxanthine was 20-fold more potent than theophylline at the A1 receptor and 5-fold more potent at the A2 receptor.
Δεν το εξιγας μια μιας και δεν εχω το προφισενσι:green::P...Αυτο που κατάλαβα ειναι οτι αν δεν μπορείς τη καφεΐνη άστο καλύτερα:green:
Εν τελη πως το βλεπεις????Εμενα παντος μου φεντε πολυ δυνατο αλλα πιστεύω δεν εχει νόημα να σου πιραζει τον θυροειδή.....γιαυτο και δεν θα το δοκιμάσω....:unsure:
μμμ,αλλος ενας λιπδιαλυτhς που πουλανε σαν prewo:green:
μμμ,αλλος ενας λιπδιαλυτhς που πουλανε σαν prewo:green:
Ααααα γεια σου...Εσύ μιλάς σωστά:green::green::green:Και εγώ αυτό προσπαθώ να πω τόση ώρα:green:....
Δεν το εξιγας μια μιας και δεν εχω το προφισενσι:green::P...Αυτο που κατάλαβα ειναι οτι αν δεν μπορείς τη καφεΐνη άστο καλύτερα:green:
Εν τελη πως το βλεπεις????Εμενα παντος μου φεντε πολυ δυνατο αλλα πιστεύω δεν εχει νόημα να σου πιραζει τον θυροειδή.....γιαυτο και δεν θα το δοκιμάσω....:unsure:
υπερβολικο.... το εχουν ξεφτιλισει με τα stims....
creatyl-l-glutamine αλλο και τουτο :green::P:P
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